Spiked samples blind analysis should fall between 80-120. Which option correctly states this range?

Spiked samples blind analysis should fall between 80-120. Which option correctly states this range?

• A. 60-100
• B. 70-100
• C. 80-120
• D. 90-140

Answer: (C)

Spiked samples are used to check accuracy by adding a known amount of analyte and seeing how much is recovered after processing. The acceptable recovery window is typically 80–120%, meaning the measured amount should be within 20% above or below the true spike amount. This range accounts for small losses or matrix effects without indicating a biased method. Values outside this window suggest under- or over-recovery and potential issues with the method or sample handling. Among the options, 80–120% is the standard acceptable range, while the others are either too low on the lower end or too high on the upper end.

Spiked samples are used to check accuracy by adding a known amount of analyte and seeing how much is recovered after processing. The acceptable recovery window is typically 80–120%, meaning the measured amount should be within 20% above or below the true spike amount. This range accounts for small losses or matrix effects without indicating a biased method. Values outside this window suggest under- or over-recovery and potential issues with the method or sample handling. Among the options, 80–120% is the standard acceptable range, while the others are either too low on the lower end or too high on the upper end.